GENETIC CLUES TO WHY WE OVEREAT
發現“貪吃”基因
Scientists have discovered one likely reason some people eat to live and others live to eat.
為什麼有些人吃東西是為了活著,而另一些人活著是為了吃?科學家們發現了一個可能的原因。
Researchers at the University at Buffalo in New York have found that people with genetically lower dopamine – a neurotransmitter that helps make activities and substances more rewarding – find food to be more rewarding than people without it. In other words, they are more motivated to eat, and they eat more.
紐約州立大學水牛城分校(University at Buffalo in New York)的de研yan究jiu人ren員yuan發fa現xian,與yu其qi他ta人ren相xiang比bi,由you於yu遺yi傳chuan因yin素su導dao致zhi體ti內nei多duo巴ba胺an含han量liang較jiao低di的de人ren覺jiao得de食shi物wu更geng令ling人ren滿man足zu。換huan句ju話hua說shuo,他ta們men吃chi東dong西xi的de動dong力li更geng足zu,吃chi的de也ye更geng多duo。多duo巴ba胺an是shi一yi種zhong神shen經jing遞di質zhi,能neng讓rang某mou些xie行xing為wei或huo物wu質zhi給gei人ren們men帶dai來lai更geng大da的de滿man足zu感gan。
The findings, which appear in Behavioral Neuroscience, offer insights that could inspire treatment programmes for obesity, and maybe even genetically targeted drugs.
這些研究結果刊登在《行為神經科學》(Behavioral Neuroscience)期刊上,由此提出的見解可能會為肥胖症治療項目帶來啟發,甚至可能為基因藥物提供靈感。
Researchers measured the body mass of 29 obese adults and 45 who were not obese. They also swabbed DNA samples from inside their cheeks, had them fill in eating questionnaires and had them perform a series of tasks.
研究人員測量了29名肥胖成年人與45名不肥胖的成年人的體重,還用棉簽從他們的臉頰內側擦取了DNA樣本,讓他們填寫關於吃東西的調查問卷,並讓他們完成一係列任務。
Both obesity and the genetic make-up associated with fewer dopamine receptors predicted a significant response to food's rewarding power. Participants for whom food was most rewarding consumed more calories. What is more, obese participants clearly found food to be more rewarding than non-obese participants.
肥fei胖pang和he與yu多duo巴ba胺an受shou體ti較jiao少shao相xiang關guan的de基ji因yin構gou造zao,都dou預yu示shi著zhe對dui食shi物wu令ling人ren滿man足zu的de力li量liang做zuo出chu強qiang烈lie回hui應ying。認ren為wei食shi物wu最zui令ling人ren滿man意yi的de參can與yu者zhe攝she取qu的de卡ka路lu裏li更geng多duo。此ci外wai,與yu不bu肥fei胖pang的de參can與yu者zhe相xiang比bi,肥fei胖pang參can與yu者zhe顯xian然ran認ren為wei食shi物wu更geng能neng帶dai來lai滿man足zu感gan。
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